Trends in Glycoscience and Glycotechnology
Online ISSN : 1883-2113
Print ISSN : 0915-7352
ISSN-L : 0915-7352
Article for JSCR 40th Anniversary Issue
Functional Roles of Glycoprotein Glycans in Neural Stem Cells
Hirokazu Yagi
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2019 Volume 31 Issue 181 Pages SE91-SE92

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Abstract

Neural stem cells (NSCs) possess high proliferative potential and capacity for self-renewal with retention of multipotency to differentiate into brain-forming cells. The glycoprotein glycans expressed on NSCs are associated with the maintenance of neural cell stemness and differentiation via several signaling pathways. Here we outline current knowledge of the possible functional mechanisms of glycoprotein glycans to determine cell fates, which are associated with their expression patterns and structural characteristic features.

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© 2019 FCCA (Forum: Carbohydrates Coming of Age)
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