Trends in Glycoscience and Glycotechnology
Online ISSN : 1883-2113
Print ISSN : 0915-7352
ISSN-L : 0915-7352
MINIREVIEW
Recombinant Glycoenzyme Production in Gram-Positive Bacteria—An Overview
Amir Hossein MohseniSedigheh Taghinezhad-SaroukalaeiJosef Voglmeir
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2020 Volume 32 Issue 187 Pages E99-E104

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Abstract

The recombinant production of glycoenzymes plays a significant role in industrial biocatalysis. The selection of an expression system which allows the high-level production of recombinant glycoenzymes using extracellular and intracellular expression, and the need for correct protein folding make Gram-positive bacteria interesting alternatives to the commonly used Gram-negative expression host Escherichia coli. In this overview we summarize recent approaches using Gram-positive bacteria as cell factories for the recombinant production of glycoenzymes, with a special focus on the optimization of glycoprotein production in lactic acid bacteria.

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© 2020 FCCA (Forum: Carbohydrates Coming of Age)
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