The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
The Effect of Autonomic Drugs on the Canine Electroureterogram
SEIGI TSUCHIDAHIROATSU SUGAWARASATOSHI MATSUMURAYOSHITAKA SHIBUYAAKINORI NISHIYAMA
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1973 Volume 110 Issue 3 Pages 235-245

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Abstract

Excluding the influence of changing urine flow by ligating the renal vein, canine electroureterographic studies were conducted to evaluate the effects of autonomic drugs upon the ureteral function. Intra-aortic administration of epinephrine, norepinephrine, phenylephrine, some amounts of acetylcholine, and dimethylphenylpiperazinium (DMPP) accelerated ureteral peristalsis. In the preadministration of phentolamine, epinephrine prolonged discharge intervals, and the response was suggestive of β effect. Phentolamine, propranolol, neostigmine, atropine, hexamethonium and tetrodotoxin caused no changes in electroureterograms.

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