1934 年 24 巻 6 号 p. 572-579
Adrenaline hydrochloride was applied to normal rabbits, in doses of 0.1-30 mgrm. per kilo when subcutaneously applied and of 4-10 mgrms. per kilo when intravenously injected. As a rule the animals were killed by a blow on the neck one hour after the end of the injection; some animals died within one hour. Soon after killing or death the suprarenal glands were excised per laparotomiam, and the epinephrine determined by means of Suto-Kojima's sublimate method.
Neither decrease nor increase was found in the epinephrine storage. We must conclude the non-influence of adrenaline upon the epinephrine load, which corresponds to the fact that adrenaline does not increase the epinephrine discharge from the suprarenal glands at all, while it depresses an exaggerated liberation, if it exists.