The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Toxic Substances in Cancer
VII. Effect on the Excised Frog Heart
Iwao YamaguchiEiji OzakiHisashi KammaKiyota Oh-Uti
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1959 Volume 69 Issue 2-3 Pages 191-196


1. Liquid acid fraction isolated from the alcohol extract of the tissue of gastric carcinoma inhibited the excised frog heart more markedly than the corresponding fraction of the normal gastric mucosa.
2. Dried powder of gastric juice of patients with gastric carcinoma and many of its fractions showed only slight inhibition to the heart.
3. Ether extract of fresh gastric juice of patients with gastric carcinoma inhibited the heart intensely while the control extract was far less effective. Of all the fractions of the extract, liquid acid fraction was the most effective in inhibition.

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