Inclusion Bodies in Hakuri

Abstract

Based on 7 Hakuri autopsies, new (?), prominent intracytoplasmic (elementary body-like particles and globular bodies) and less prominent intranuclear inclusions were demonstrated in smears from organs by Macchiavello's, Giemsa's, and Wright's stains. With the electron microscope a globular body found in the liver of a patient was proved to be composed of many virus-like particles which occluded the body. Both inclusions were most frequently detected in the mesenteric lymph nodes, the liver, the spleen, the lung, and occasionally in other organs.
The authors wish to express their gratitude to Prof. K. Hukai for the electronmicroscopic examination.
This study was aided by a grant from the Ministry of Education.