初診時糖負荷試験成績よりみた糖尿病治療方針の検討

抄録

A statistical analysis on 156 diabetic cases were performed retrospectively and the suitable treatment also predicted by the result in oral administration of 50 gm of glucose tolerance test (GTT) at the first examination.
The patients were divided into 4 groups;(1) dieted group (35 cases) controled by dietary treatment only, (2) oral drugs group (69 cases) controled by oral antidiabetic drugs, (3) insulin group (30 cases) controled by insulin, and (4) uncontroled group (18 cases) failed to any treatment.
Levels of blood sugar of GTT were examined to 70 per cent of patients and, the data were given as follows: The “dieted group”, below 120 mg% at the fasting, below 200 mg% at the 1st hour, below 200 mg % at the 2nd below 120 mg % at the 3rd hour. The “oral drugs group”, 150-200 mg % at the fasting, 250-350 mg % at the 1st hour, 250-350 mg % at the 2nd hour and 150-250 mg % at the 3rd hour.Both “insulin group” and “uncontroled group” were over 250 mg % at fasting, over 400 mg % at 1st hour, over 400 mg% at the 2nd hour and over 350 mg % at the 3rd hour.
Reliabilities of the above mentioned criteria for “insulin group” was increased in case of lean, juvenile and hypercholesterolemia or suffering from cataracta. The “dieted group” also gives the believable data of the patient without lean, juvenile and hypercholesterolemia.
Nevertheless the insulin therapy always demonstrated in diabetitcs under condition of criteria of “insulin group.” But the steps of treatment is still very important which should be kept in mind by the order of diet, oral drugs and insulin administration.