抄録
We observed 27 females who gave birth to large babies and 27 females who had normal babies. The following results were obtained by the examination of prediabetic syndome, reference to glucose metabolism, seven days before or after birth:
1) Lowering in the glucose tolerance was noted in females who had large babies in comparison to those in the contrast group.
2) The birth rate of large babies in females who had such babies was 58.8%. And it was presumed that the higher rate was obtained in the second children than the first children. The average birth weight of the normal babies of 27 females was 2908 g. That of the large babies, on the other hand, was 3785 g.
3) A considerably high rate of abortion (23.4%) was observed in females with large babies.
4) Many mothers' milk of large babies flowed well.
5) Many females who had large babies were of an obese type.
6) Of females with large babies, 3 cases (11.0%) were from diabetic families. Of those, 2 cases proved to be positive to the cortison-glucose tolerance test.
7) The same female with large babies gave birth to two malformed children.