2001 年 14 巻 1 号 p. 59
Recently, much has been focused on the potential for a wide range of chemicals to interact with the disruption of the endocrine system in humans and animals. Some of those chemicals have been implicated as endocrine disrupting chemicals (EDCs). We represent this review that the current endocrine systems including of molecular biology and effects of EDCs are discussed, as examples pituitary and mammary gland. Alterations to the endocrine environment caused by EDCs may occur through interference with the synthesis, secretion, transport, binding, action, or elimination of natural hormones responsible for vital homeostasis, differentiation, development, reproduction, and/or behavior. It is important consideration for assessing the adverse effects of EDCs to have an understanding of normal endocrine systems, subsequently, dose, duration of exposure, age, sex, situation, and frequency are estimated.
