原始地球におけるRNAの化学的起源の探求　－リボヌクレオシドの前生物的合成－

抄録

  RNA World is a one of the widely accepted hypotheses for the origin of life. To hold the validity of the hypothesis, the synthetic pathways which provide RNA building blocks under prebiotically plausible conditions must be demonstrated. The separate pathways to purines and pyrimidines have been reported so a far, but their concurrent syntheses remain a critical issue. Here we describe our recent research on the unified prebiotic synthesis of the pyrimidine and purine nucleosides from small molecules and ribose driven by wet-dry cycles.