抄録
White male rabbits were divided into 2 groups, and injected with thiamine or thiaminepropyldisulfide 2 mg per kilogram daily, for several days. The animals were killed at 36〜40 hours after the last injection and the thiamine contents in the blood and the neural tissues were measured. The concentration of thiamine in the blood did not increase even after 60 days of consecutive administration. Thiamine in the neural tissues was increased with successive administration and its tendency was more pronounced in the thiaminepropyldisulfide group than the thiamine group.