シロネズミのCoenzyme A代謝におよぼす食餌組成の影響 : (III)離乳期シロネズミのCoenzyme A代謝におよぼす蛋白同化ステロイドの影響

抄録

When the weaning rats were fed on 20% casein diet for 14 days and were injected 0.2mg or 1.0mg of NPP (19-norandrosterone phenyl propionate) in 4 divided dose, the body weight and hepatic CoA concentration were unchanged or slightly reduced as compared with control. Weaning rats, fed on 5% casein diet for 10 days and on 20% casein for another 10 days, were injected of 0.15mg or 0.75mg of NPP in 3 divided dose. In these groups body weight and hepatic CoA were also unchanged. But in both dietary groups the serum protein and liver nitrogen were increased by the injection of 1.0mg or 0.75mg of NPP. In the group, fed on 5% casein diet alone for 14 days, the body weight, serum protein and liver nitrogen were not altered by administration of NPP. By the injection of 1.0mg NPP under the low potein condition, it was observed that the hepatic CoA concentration revealed a tendency to increase. Oral administration of HMD (2-hydroxymethylene-17α-methyl-dihydro testosterone) did not show a remarkable effects on the body weight, serum protein, liver nitrogen and CoA.