Abstract
In order to establish the method of the determination of vitamins A and E in the presence of each other, the procedure of hydrogenation of vitamin A described in USP XVII was re-examined. Hydrogenation of vitamin A with 5% Pd-CaCO_3 as catalyser was proceeded smoothly under atmospheric pressure at room temperature. Pd-CaCO_3 was prepared by the procedure of M. Busch with a slight modification. Mixed samples of vitamins A and E were assayed using the hydrogenation method to avoid interference from each vitamins. This method gave quantitative recovery of vitamins A and E.
