2019 年 62 巻 8 号 p. 516-521
Scanning probe electrospray ionization (SPESI) enables the ambient sampling and ionization of molecules in a solid material by utilizing charged nano-volume liquid with a capillary probe. In order to understand the dynamic change of charged nano-volume liquid at the end of capillary probe, the probe displacement and the mass spectra during a single sampling and ionization process were measured simultaneously. It was found that the dynamic behavior of liquid bridge was affected by the physical properties of solvents. The time to break a liquid bridge was positively correlated with the surface tension of solvent while the time from the breakage of liquid bridge to the detection of sample ions was positively correlated with the viscosity of solvent.