YAKUGAKU ZASSHI
総説
脳回路システムにおける薬効評価系を目指した多ニューロン画像法
池谷 裕二
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ジャーナル フリー

128 巻 (2008) 9 号 p. 1251-1257

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  Functional multineuron calcium imaging (fMCI) is a large-scale optical technique that records the suprathreshold activity from large neuron populations. fMCI has several advantages, including: i) simultaneous recording from hundreds of neurons, ii) single-cell resolution, iii) identifiable location of neurons, and iv) detection of non-active neurons during the observation period. I review the principle and detailed method of fMCI and also describe the effect of oseltamivir on neuronal network as an example for practical application of fMCI.

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© 2008 by the PHARMACEUTICAL SOCIETY OF JAPAN
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