J-STAGE トップ  >  資料トップ  > 書誌事項

YAKUGAKU ZASSHI
Vol. 130 (2010) No. 12 P 1687-1694

記事言語:

http://doi.org/10.1248/yakushi.130.1687

誌上シンポジウム

  The cell-killing effect of boron neutron capture therapy (BNCT) is due to the nuclear reaction of two essentially nontoxic species, boron-10 (10B) and thermal neutrons, whose destructive effect is well observed in boron-loaded tissues. High accumulation and selective delivery of boron into tumor tissue are the most important requirements to achieve efficient neutron capture therapy of cancers. This review focuses on liposomal boron delivery system (BDS) as a recent promising approach that meet these requirements for BNCT. BDS involves two strategies: (1) encapsulation of boron in the aqueous core of liposomes and (2) accumulation of boron in the liposomal bilayer. In this review, recent development of liposomal boron delivery system is summarized.

Copyright © 2010 by the PHARMACEUTICAL SOCIETY OF JAPAN

記事ツール

この記事を共有