製剤学的研究を通じ臨床現場に貢献できる薬剤師の養成を目指して

抄録

 In clinical environments, difficulty in the uniform preparation of Mohs paste has been noted, due to variations in its physical properties, and despite preparations being based on the same prescriptions. Therefore, studies have been conducted to clarify the physicochemical phenomena influencing such variations, and then to develop a prescription design that will improve the usability of this product through the use of additives with sufficient safety, thereby addressing the above-mentioned demerit. An improved form of Mohs paste, not containing the starch that is responsible for the variations in physical properties, was developed in consideration of appropriate bases, and its pharmacological mechanisms were examined, with a focus on its hemostatic effects. Furthermore, clinical training regarding reliably consistent Mohs paste preparation was provided in medical institutions performing collaborative drug therapy management (CDTM).