In Japan there are concerns that there will be a surge in social insurance costs such as medical and nursing care expenses as a result of the baby boom generation reaching the late stages of old age (75 years old and beyond) around 2025 (“The 2025 Problem”). In 2012, the “Outline on Social Insurance and Tax Reform” was approved by the Japanese cabinet and government, including “construction of regional comprehensive care”. To promote participation in home medical care by pharmacists, this article presents the roles demanded of pharmacists in regional comprehensive care from the standpoint of physicians, and the discussion of case studies bridging the gap from knowledge learned in lectures to practical applications. In the field of medical education, “The 2023 Problem”, regarding standards of education on a global level, caused medical schools across Japan to scramble for curriculum reform, specifically in the demand for increased time spent in clinical training and the expansion of community-based medical education. The current state of community-based medical education will be reviewed. In light of these developments, “the working group to create home clinical cases for education” was developed by clinical pharmacists in the field and university faculty members at Daiichi University of Pharmacy.