微生物由来医薬品骨格生合成酵素の発掘とその利用

抄録

Natural products are an important source of medicinal seeds. The discovery of novel biosynthetic enzymes from nature is important for their use as biocatalysts for the enzymatic synthesis of useful natural products. In this review, I describe our recent research on the exploitation of a novel secondary metabolite enzyme and the production of unnatural bioactive products in the microbial host, as presented in the S02 symposium in the 141st annual meeting in the Pharmaceutical Society of Japan.