YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
6位および7位置換3-Aminoisocarbostyril誘導体の合成(第2報)3-Alkylamino-および3-Arylamino-isocarbostyril誘導体の合成
合屋 周次郎高館 明田中 利明鶴田 由美子緒方 春美
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1980 年 100 巻 8 号 p. 826-831

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3-Alkylamino- and 3-arylamino-isocarbostyril derivatives were synthesized in order to investigate their fluorescent properties. Reactions of (2-cyanomethyl) benzoic acid derivatives (Ia-Ie) with primary amines (cyclohexylamine, benzylamine, and aniline) in chlorobenzene gave the corresponding 3-substituted aminoisocarbostyrils (IIa-IIo) having methoxy or chloro groups at the 6- and/or 7-positions. 3-Alkylaminoisocarbostyrils (IIa-IIc, IIf-IIh, and Va-Vf) were also given by reactions of methyl 2-(2'-ethoxy-2'-iminoethyl) benzoates (IVa-IVc) with alkylamines (methylamine, dimethylamine, cyclohexylamine, and benzylamine) in aqueous solution.

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