Some N, N-dialkylglycylbenzhydrylamides were synthesized. Phthaloylglycine was condensed with benzhydrylamine in the presence of DCC to give 4, which was treated with hydrazine hydrate to give 3a. The dialkylamides, 3b-3e, were obtained by the reaction of chloroacetylbenzhydrylamine with the corresponding secondary amines. In antihistaminic tests the compounds, 3b-3e, showed weak activities.
