YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
9位置換-Benzo[α]phenoxazine誘導体の抗腫瘍性, 抗菌性および抗真菌性
本橋 登
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ジャーナル フリー

1982 年 102 巻 10 号 p. 992-994

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Studies were made on the biological activity of ten 9-diethylaminobenzo [α] phenoxazonium salts (BPZ). (1) 9-Diethylaminobenzo [α] phenoxazonium nitrate (1) was found to have a high antitumor effect on Ehrlich carcinoma. (2) 1 and 9-diethylamino-5-phenylsulfonylbenzo [α] phenoxazonium nitrate (2) were found to have some antitumor effects on RADA 1 Leukemia cell. (3) 9-Diethylamino-5-(3-methylphenylthio) benzo [α] phenoxazonium nitrate (9), 9-diethylamino-5-(4-methylphenylthio) benzo [α] phenoxazonium nitrate (10), 9-diethylamino-5-phenylthiobenzo [α] phenoxazonium nitrate (4) and 9-diethylamino-5-(2-methylphenylthio) benzo [α] phenoxazonium nitrate (8) were found to show some antibacterial effects on Staphylocoocus aureus 209 P.

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