YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
水溶液中におけるグリチルリチンの物理化学的性質(第5報)グリチルリチンとコール酸ナトリウムとの混合溶液の臨界ミセル濃度
米澤 頼信砂田 久一大塚 昭信中垣 正幸
著者情報
ジャーナル フリー

1983 年 103 巻 10 号 p. 1085-1090

詳細
抄録

Critical micelle concentrations (cmc) of the mixed solutions of glycyrrhizin and sodium cholate were determined by the measurements of light absorption of aqueous iodine solution and solubility of yellow-OB as well as the measurements of surface tension. Critical micelle concentrations of the mixed solutions determined by these methods were relatively in good agreement with each other. The cmc increased with increasing the mol fraction of sodium cholate and pH. It was found that the cmc of mixed solutions and the composition of mixed micelles were in conformity with the theory of ideal mixing. The facts suggest that glycyrrhizin contributed effectively to the formation of mixed micelle. The mol fraction of glycyrrhizin in mixed micelle increased with decreasing pH.

著者関連情報
© by the PHARMACEUTICAL SOCIETY OF JAPAN
前の記事 次の記事
feedback
Top