YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ヒノキチオールおよび7-ヨードヒノキチオールのメチル化とヒドラジノトロポン誘導体および5-アミノヒノキチオールのSchiff塩基の合成
神代 昭藤田 俊生播磨 由紀子佐伯 栄子米田 文郎
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1983 年 103 巻 12 号 p. 1303-1312

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Methylation of hinokitiol and 7-iodohinokitiol yielded two isomeric methyl ethers by the ratio of about 1 : 1, respectively. The proton and 18C nucleo magnetic resonance spectra of methyl ethers of 7-iodohinokitiol were discussed to elucidate the structures. Isomers of hydrazino-isopropyl-tropone and hydrazino-iodoisopropyl-tropone were obtained by the reaction of the corresponding methyl ethers with hydrazine hydrate. Series of Schiff bases were synthesized by condensation of aromatic aldehydes with these hydrazinotropones and 5-aminohinokitiol, respectively.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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