YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
β-シクロデキストリン包接による7位置換クマリン誘導体の螢光挙動
高舘 明藤野 博之合屋 周次郎平山 文俊小田切 優樹上釜 兼人山口 裕之
著者情報
ジャーナル フリー

1983 年 103 巻 2 号 p. 193-197

詳細
抄録

The inclusion complexes of 7-substituted coumarin derivatives (7-hydroxy-, 7-amino-, 7-dimethylamino-, 7-methoxy-, and 7-ethoxy-4-methylcoumarins) with β-cyclodextrin in aqueous solutions were formed. The equilibrium constants of these complexes were obtained by fluorescence and circular dichroism spectrophotometric methods. Fluorescence enhancement or quenching was observed upon inclusion of coumarin derivatives with β-cyclodextrin. The fluorescent behavior was discussed from the standpoint of the solvent effect of coumarin derivatives and of the geometry of the inclusion complexes assumed from their 1H nuclear magnetic resonance spectra.

著者関連情報
© by the PHARMACEUTICAL SOCIETY OF JAPAN
前の記事 次の記事
feedback
Top