ガジュツ末の消化器系におよぼす薬理作用

抄録

Pharmacological effects of the powder prepared from the dried subterranean stem from Curcuma zedoaria ROSCOE, which was cultivated in Japan, on the gastrointestinal tract of experimental animals were examined. Oral administration of the above-mentioned powder (C.Z.) significantly inhibited the intestinal transit of charcoal in mice, significantly increased the bile secretion in rats and slightly inhibited the stomach secretion in rats. The effect of C.Z. on the bile secretion lasted longer than that of dehydrocholate. Water soluble fraction of C.Z. exerted nonspecific inhibition on the contractile responses of the isolated rat duodenum and ileum to acetylcholine, histamine and potassium ion and caused the inhibition of the spontaneous movements and the relaxation of the isolated rat duodenum and ileum.