YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Ca2+-Blocker作用を有する天然物のScreening試験結果及びジャショウシの活性成分
山原 條二三木 修治村上 秀樹沢田 徳之助藤村 一
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1985 年 105 巻 5 号 p. 449-458

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As a study to develop new drugs from natural source, Ca2+-blocking action which is expected to be effective for hypertension was examined for over 1500 plants including Japanese and Chinese herbal medicines, and the results are described in this report. Among these medicines, Cnidii monnieri, a Chinese harbal medicine, was found to be most effective in the initial screening test. Its active principal was found to be osthole, a coumarin derivative.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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