YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
タキキニン・ペプチドとその生理的役割
高野 行夫神谷 大雄
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1988 年 108 巻 3 号 p. 201-214

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Within the past decade, more than 30 peptides have been identified in the central nervous system (CNS). Of all these peptides, substance P (SP) is one of the best characterized neuropeptides in the mammalian tissues. In addition to SP, two novel tachykinin peptides have recently been identified in the mammalian CNS, namely neurokinin A and neurokinin B. This review will describe our present knowledge on the distribution of tachykinins, its pharmacological properties, especially tachykinins peptide receptors and cardiovascular effects in the CNS.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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