YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
各種生薬メタノールエキスのラットα-Naphthylisothiocyanate(ANIT)肝障害防護効力
熊沢 紀子太田 節子塗 修華鴨川 旭篠田 雅人
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1991 年 111 巻 3 号 p. 199-204

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Sixty seven methanol extracts of crude drugs were examined for their effects to protect hepatic injury induced by α-naphthylisothiocyanate (ANIT) in rats. In terms of the release of intrahepatic enzymes and bilirubin into the serum, 19 extracts were found to suppress the increase in the concentration of serum bilirubin by ANIT. Out of the 19 extracts those of Berchemia Racemosa Caulis, Aurantii Nobilis Pericarpium, Polygoni Avicularis Herba and Gentianae Scabrae Radix, also inhibited the release of several intrahepatic enzymes used as parenchymal injury parameter.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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