1949 年 69 巻 12 号 p. 555-557
Esters of p-toluenesulfonic acid of aminoalcohols such as α-diethylamino-δ-pentanol which has a tertiary nitrogen atom of strong basicity cannot be prepared by the ordinary method of esterification for p-toluenesulfonic acid. It is necessary, in these cases, to close the basicity of its tertiary nitrogen atom by salt formation and then reacting for a long period of time at a comparatively high temperature. The author has found that the α-diethylamino-δ-pentylation of the amino group of aniline or 6-methoxy-8-aminoquinoline by the use of this ester cannot be carried out by the method described in D.R.P. and that it is necessary to use a much higher temperature and a longer reacting time.