P-アミノメチルベンゾールスルホンアミドの體内變化に就て
1949 年 69 巻 3 号 p. 122-123
詳細
1949 年 69 巻 3 号 p. 122-123
Extraction by AoOEt of NH3-alkalized human urine obtained from men given p-aminomethylbenzene sulfonamide hydrochloride gives p-acetylaminomethylbenzene sulfonamide, m.p. 171-2°. Evaporation of the residual urine under reduced pressure and subsequent digestion of the residue with EtOH gives p-sulfonamido-benzylurea, m.p. 192-3°. This compound is believed to be the result of the condensation with urea during evaporation of p-aminomethylbenzene sulfonamide excreted into urine in its free form although the latter was not obtained as such.
