フラン誘導體の合成研究 (第3報)

抄録

During the course of syntheses of furan derivatives of antibacterial properties, the authors designated those substances having one or more “antibacterial group”, i.e. nitro and halogen radicals, in one molecule as an “antibacterial body” and those atomic groups assumed to affect changes in the activities or selectivities of the bacteria, the “auxo-antibacterial group”. It was found that the antibacterial activity diminished greatly when the nitro-radical in 2-(5-nitro)-furaldehyde semicarbazone was substituted by Clatom. The new compound, 2-(5-nitro)-furylacrolein semicarbazone, possesses uniform antibacterial activity comparable to 2-(5-nitro)-furaldehyde semicarbazone.