YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Specificity of Sulfamine Type Compounds (Ishidate-Okano). V
Antagonism between p-Nitraniline and p-Aminobenzoic Acid
Sadasuke Okano
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1950 年 70 巻 7-8 号 p. 435-439

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Bacteriostatic action of p-nitraniline was found to be reversed by p-aminobenzoic acid (antagonism coefficient: ca. 2, 500). The action of p-aminobenzene-antimonic acid, and that of ortho and meta isomers of nitraniline, however, were not reversed by p-aminobenzoic acid. Mechanism of specific antagonism between p-nitraniline and p-aminobenzoic acid was discussed.
Thermal analyses showed that p-nitraniline and p-aminobenzoic acid formed molecular compound (1:1) and m-nitranline and p-aminobenzoic acid formed no compound.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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