Qualitative Reaction of Active Methylene Group. II

Reaction of 1, 2-Naphthoquinone-4-sulfonic Acid with Active Methylene and Primary Amines

抄録

1. 1, 2-Naphthoquinone-4-sulfonate with active methylene compounds at room temperature forms two kinds of condensate according to the acidity of the methylene groups, the one is 1 or 2-quinonide of the naphthoquinone sulfonate containing sulfonic group, and the other, 4-derivative of 1, 2-naphthoquinone, not containing sulfonic acid.
2. With primary amines, the same reagent also forms the two types of amido-derivatives, the one being a condensate at 1- or 2-position, the other, a condensation product at 4-position containing no sulfonic group. The reaction mechanism is discussed.