1951 年 71 巻 10 号 p. 1043-1046
When cycleanine (I) is reacted with metallic sodium in liquid ammonia, it is bisected into l-1-(4′-hydroxybenzyl)-6, 7-dimethoxyl-N-methyl-1, 2, 3, 4-tetrahydroisoquinoline (l-armepavine) (II). Therefore, it has been confirmed that the structure of cycleanine and the steric configuration of the two asymmetric centers in the molecule must be represented by (I).