YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
試驗管内に於ける結核菌に対する諸種化合物の影響に関する研究 (第1報)
内藤 益一瀧 長次志保田 明藤川 福二郎中島 邦夫藤井 博徳岡 曉正岡本 正夫
著者情報
ジャーナル フリー

1951 年 71 巻 2 号 p. 113-115

詳細
抄録

The influences of some drugs upon M. tuberculosis and the measurement of the amount of oxygen consumption, measured by the Warburg's manometer, and at the same time, the growth inhibiting activities using Kirchner's culture medium, in which 10% of serum was added, were compared. 31 compounds were tested; i.e. 10 of resorcinol compounds; 7 of lichen, substances 6 of coumarin compounds, 8 of plant components and synthesized products. There are many types in consuming oxygen, and among them usnic acid, monochlorocyclohexylresorcinol, showed the strongest inhibiting action to oxygen consumption. Usnic acid and p-aminosalicylic acid were the strongest in inhibiting growth, 2, 4-dihydroxy-3-chloro-5-n-amylbenzaldehyde, 2, 4-dihydroxy-3-chloro-5-n-hexylbenzaldehyde followed these products. It was shown that the inhibiting action to oxygen consumption and the growth inhibiting activities were not always parallel.

著者関連情報
© by the PHARMACEUTICAL SOCIETY OF JAPAN
前の記事 次の記事
feedback
Top