YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
チアツォール誘導体の研究 (第2報)
2-Amino-4-methyl-5-β-hydroxyethylthiazoleの脱アミノ反應
武田 健一川崎 和彦
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1951 年 71 巻 2 号 p. 84-86

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It was found that 4-methyl-5-β-hydroxyethylthiazole can be synthesized from 2-amino-4-methyl-5-β-hydroxyethylthiazole in a good yield. 2-Bromo-4-methyl-5-β-hydroxyethylthiazole is obtained by thermal decomposition of diazoperbromide of 2-amino derivative of the starting material, and its reduction easily yields the objective 4-methyl-5-β-hydroxyethylthiazole.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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