Coumarin-3-carboxylic Acid及び3, 4-Dihydrocoumarin-3-carboxylic Acidの塩基性誘導体の合成

抄録

Being interested in the physiogical proparties of coumarin-carboxylic acid derivatives, following were synthesized: Coumarin-3-carboxylic acid dimethyl amide (m.p. 145°) and its 3, 4-dihydro derivative (m.p. 75°); coumarin-3-carboxylic acid diethyl amide (m.p. 78°) and its 3, 4-dihydro derivative (b.p.₇ 143°); β-dimethylaminoethyl coumarin-3-carboxylate (m.p. 82°) and its 3, 4-dihydro derivative (b.p._0.3 87°, picrate, m.p. 137° (decomp.)); β-diethylaminoethyl coumarin-3-carboxylate (m.p. 68°) and its 3, 4-dihydro derivative (b.p._0.9 89°, dipicrolonate, m.p. 141° (decomp.)). Their physiological properties are still under investigation.