含硫黄ピリヂン誘導体に就て (第31報)
ピリドチアゾール類及びピリドオキサゾール類の合成
1951 年 71 巻 3 号 p. 169-172
詳細
1951 年 71 巻 3 号 p. 169-172
Application of cupric or potassium thiocyanate and bromine to 2-aminopyridines does not yield pyridothiazole ring, but the same reaction on 2, 6-diaminopyridines and 3 (5)-aminopyridines yields pyridothiazole rings. Corresponding pyridothiazoles were synthesized from 2-hydroxy-5-aminopyridine, 2-alkyloxy-5-aminopyridines and 2, 5-diaminopyridine. 2-Amino-3-nitropyridine was converted into 2-hydroxy-3-nitro-5-bromopyridine, reduced to 2-hydroxy-3-amino-5-bromopyridine and, by heating with acetic anhydride, it was cyclized to pyridoxazole.
