YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Syntheses of p-Nitrophenyl-ketones. I
Synthesis of p-Nitro-acetophenone
Shigehiko SugasawaNorio SugimotoJun-ichi IwaoYutaro Nakamura
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1951 年 71 巻 4 号 p. 225-226

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p-Nitro-acetophenone, an important starting material for the synthesis of chloramphenicol, was prepared from p-amino-acetophenone by the Sandmeyer's reaction in a 65% yield. This method will be recommended for its simplicity in manipulation and also from the economical view-point.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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