檜葉油成分について

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Investigations were carried out on the Hinoki Leaf Oil, an essential oil from the leaves of Chamaecyparis obtusa, and a new component, d-terpinyl acetate, was found besides the well-known components of pinene, limonene, bornyl acetate, sesquiterpene and sesquiterpene alcohol. Hinokic acid, m.p. 166°, contained in the acid portion, was founc to correspond to C₁₅H₂₂O₂ from its analytical values, rather than the previously proposed C₁₅H₂₄O₂. The acid is monobasic, contains two double bonds and gives a tetrahydro compound of m.p. 153°. It was assumed that the chemical structure of hinokid acid would be a bicyclic sesquiterpene-carboxylic acid possessing two double bonds. It was also observed that this acid was effective in inhibiting the growth of Mycobacterium tuberculosis (avian type) in vitro, at about 1:10000 dilution.