α-Acylaminoacetophenone was synthesized from acetophenoxime p-tosyl ester by a reaction similar to the Beckmann rearrangement, from sodium hippurate by the application of benzoic anhydride, or from 2-phenyl-5 (4H)-oxazolone by the application of benzoyl chloride. Aldol condensation and the Pondorf reduction of the ketone compound yielded dl-threo-1-phenyl-2-acylamino-1, 3-propanediol.
