YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Decomposition of Benzylamine Derivatives. II
Genshun SunagawaTeishiro KushimaTakeshi Ichii
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1952 Volume 72 Issue 12 Pages 1570-1574

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Abstract
1) The benzylamine derivatives possessing a substituent with comparatively strong -E effect in the para-position, such as the methoxyl, and an aromatic residue bonded to its nitrogen, easily undergo decomposition by acids.
2) Respective decomposition by hydrochloric acid of 2-p-methoxybenzylaminopyrimidine and p-methoxybenzylaniline yielded α-aminopyridine, 2-anzinopyrimidine, and aniline, as the bases, with p, p′-dimethoxydiphenylmethane and formaldehyde.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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