抗結核製剤の合成 (第2報)
サリチル酸ヒドラチッド及びその関連化合物の抗菌作用
1952 年 72 巻 12 号 p. 1646-1648
詳細
1952 年 72 巻 12 号 p. 1646-1648
Several kinds of acid hydrazides were prepared and their antibacterial action in vitro was examined. As shown in Table III, p-aminosalicylic acid hydrazide was found to be far more effective than isonicotinic acid hydrazide against Mycobacterium tuberculosis. It was also pointed out that, in order for acid hydrazide to show any effective antitubercular action, the presence of a double bond in the α-position of the carbonyl would be one of the requisites.
