A Simplified Isoquinoline Synthesis. I
1952 年 72 巻 2 号 p. 252-254
詳細
1952 年 72 巻 2 号 p. 252-254
A simplified isoquinoline synthesis is described. In this method one mole each of appropriately substituted β-phenethylamine and acid were mixed under toluene and the mixture was boiled with an excess of phosphoryl chloride, giving isoquinoline in a fair yield. The isolation of the intermediate acid amide in the usual Bischler-Napieralski Perkin method was thus made unnecessary.
