A New Method for the Preparation of Secondary Amines. I

Synthesis of Aliphatic Secondary Amines

抄録

Saccharine was found to be a suitable starting material for the preparation of alkyl and aralkyl secondary amines, according to the schema shown on page 211 (I-VI). It is not necessary to isolate intermediate III, IV and V. The readiness of the last-stage hydrolysis (V-VI), when compared with that of usual arylsulfone dialkylamide is to be emphasised. Ten kinds of both alkyl- and aralkyl-amines were prepared. It was proposed to call this “Saccharine method.”