抗ヒスタミン剤の合成研究 (第1報)
4-(N-Benzyl-N-dimethylaminoethyl)-aminoantipyrineの合成
1952 年 72 巻 3 号 p. 346-347
詳細
1952 年 72 巻 3 号 p. 346-347
In order to obtain antihistaminics of ethylene diamine type possessing a pyrazolone nucleus, 4-benzylaminoantipyrine and dimethylaminoethyl chloride hydrochloride were reacted in alcohol in the presence of alkali carbonate by which 4-(N-benzyl-N-dimethylaminoethyl)-aminoantipyrine hydrochloride, m.p. 216-217°, was obtained.
