1952 年 72 巻 7 号 p. 916-919
In the synthetic preparation of 3-alkyl-4-methyl- or 4-alkyl-7-hydroxycoumarins by the condensation of resorcinol and ethyl α-alkyl- or γ-alkyl-acetoacetate in sulfuric acid, the reaction is somewhat obstructed when the ester possesses a higher alkyl group, resulting in the sulfonation of resorcinol with consequent decrease of the yield. By the decrease of sulfuric acid concentration and allowing longer hours for the reaction period, objective compounds with several long-chain alkyl groups were obtained with good yields.