抗酸性菌に対する化学療法剤の研究 第5報
2-Mercapto-5-nitropyridineの抗菌力について
1952 年 72 巻 8 号 p. 1022-1024
詳細
1952 年 72 巻 8 号 p. 1022-1024
Since 2-mercaptob-5-nitropyridine showed a strong antibacterial activity against avian type tubercle bacilli among the thiol compounds tested, its activities against various bacteria were tested (Table III). It was learned that the pyridine derivatives possessing hydroxyl or amino group in the p-position of the nitro group hardly showed any antibacterial activity (Cf. Table I), while pyridines possessing thiol group alone showed activities against both gram-positive and -negative bacteria. None of these compounds were found to be antagonized by p-aminobenzoic acid, methionine, cysteine or cystine (Table II), and were not precipitated by other than Cd... Studies are being continued as to the antibacterial activities, toxicity and the mechanism of such activities of allied. compounds.
