イソシトロネロールの合成 (第1報)
1952 年 72 巻 9 号 p. 1172-1174
詳細
1952 年 72 巻 9 号 p. 1172-1174
As one method of utilizing the levulic acid obtained as a by-product of amino acidd industry, synthesis of a perfume was attempted. Starting with ethyl levulate and isoamyl bromide, 4, 7-dimethyl-1, 4-octanolide was obtained by the Grinard reaction, and subsequent ring cleavage, dehalogenation, esterification and reduction yielded the isomer of the objective citronellol, 4, 7-dimethyl-3-octan-1-ol (isocitronellol). This was confirmed by deriving it to the semicarbazone, m. p. 86-88°, of levulic ester.
